Hey, This is Neeladri Sen, an Int PhD Student who joined the lab for pursuing
PhD in December 2014.
Completed my Bachelors of Science(Microbiology) from St. Xavier's, Kolkata in
Other than this, in free time I can keep myself glued to T.V./Laptop watching
cartoons,movies or shows.
In addition, I have some interest in painting too.
Current: Research Associate – Prof. Christine Orengo, UCL
My PhD was on “Characterizing Protein Surfaces for Binding Associations”.
During my PhD we created a library of protein-protein and domain-domain interfaces and studied the interfaces structurally.
We also studied coiled-coil interfaces to identify and score such interfaces.
In addition, I studied the physico-chemical properties of interfaces to develop a scoring scheme to distinguish between native and non-native interfaces.
I also developed a decision tree based scoring scheme to identify hotspot residues at interface.
Along with studying protein-protein interfaces, we also studied protein-small molecule interface to predict and identify off target proteins for drugs.
I was also a part of the team to predict and identify inhibitors against the Nipah proteome.
In addition, we also developed environment dependent substitution matrices and used it to predict deleterious mutations.