Topology Independent Comparison of Biomolecular 3D Structures
The performance of CLICK, in terms of structure overlap values, over 9537 pair-wise alignments collated from the HOMSTRAD database. CLICK values are compared to those of a) HOMSTRAD, b) MUSTANG, and c) SALIGN. The red diagonal line separates the cases where CLICK was better than or worse than the method compared.
The comparison of the structure overlap values of CLICK against HOMSTRAD (white square), MUSTANG (red diamond), Geometric Hashing (blue triangle), DALI (yellow triangle), and SALIGN (brown triangle) over the 64 difficult pair-wise alignments from the HOMSTRAD database.
The comparison of the structure overlap values of CLICK against MUSTANG (red diamond), Geometric Hashing (blue triangle), and DALI (yellow triangle) over 89 pair-wise alignments that are structurally similar but topologically different.