Z Score cutoff for protein structures
Z Score cutoff for DNA, RNA and DNA-Protein structures
The plots of distributions of average structure overlap
(within cut-off distances of 1Å, 2Å, and 3Å) of 435 pairwise
alignments (all-against-all) of 30 randomly chosen structures
from protein (A), DNA, RNA, and DNA-protein databases (B).
The black lines show the average structure overlap at Z-score = 2.5
for the protein, DNA, RNA, DNA-protein databases. For the protein database
(Figure 1A), the distribution of pairwise alignments of randomly chosen
structures is in blue, and the distribution of 60 difficult pairwise alignments
of homologous proteins (30% < SO < 70% and RMSD > 2.5Å) from HOMSTRAD database
(http://tardis.nibio.go.jp/homstrad/) is in red. For the other databases (Figure 1B),
the distribution of pairwise alignments of DNA, RNA, and DNA-protein is in purple,
cyan, and green, respectively.